Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.51 |
| ▸ | F2 | P00734 | 11/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.43 |
| ▸ | PLG | P00747 | 5/20 | 0.42 |
| ▸ | PLAU | P00749 | 5/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 5/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130348 | 0.91 | F10 (0.50) | F10F2PRSS1PLGPLAU | |
| Hydrochloric Acid SCHEMBL6130310 | 0.90 | F10 (0.49) | F10F2PRSS1PLGPLAU | |
| Hydrochloric Acid SCHEMBL6130303 | 0.89 | F10 (0.49) | F10F2PRSS1PLGPLAU | |
| Hydrochloric Acid SCHEMBL6130304 | 0.89 | F10 (0.49) | F10F2PRSS1PLGPLAU | |
| SCHEMBL7039059 | 0.86 | F10 (0.50) | F10F2PRSS1PLGPLAU | |
| SCHEMBL6130341 | 0.86 | CHRM3 (0.42) | F10F2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL6316344 | 0.85 | CHRM3 (0.42) | F10F2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL6130388 | 0.81 | F10 (0.47) | F10F2PLGPLAUST14 | |
| Hydrochloric Acid SCHEMBL6130309 | 0.81 | F10 (0.48) | F10F2PRSS1PLGPLAU | |
| Hydrochloric Acid SCHEMBL6130321 | 0.80 | F10 (0.48) | F10F2PRSS1PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053967-A1 | 3-(3-Amidinophenyl)-5-[({[1-(1-(iminoethyl)-4-piperidyl}amino)methyl]benzoic acid dihydrochloride and process for preparing the same | TEIJIN LIMITED (JP) | 2004-03-18 | — | — | US | claimed |
| EP-1363882-A4 | 3-(3-AMIDINOPHENYL)-5- ( 1-(1-(-IMINOETHYL)-4-PIPERIDYL AMINO)METHYL]BENZOIC ACID DIHYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME | TEIJIN LTD (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-20040053967-A1 | 3-(3-Amidinophenyl)-5-[({[1-(1-(iminoethyl)-4-piperidyl}amino)methyl]benzoic acid dihydrochloride and process for preparing the same | TEIJIN LIMITED (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1363882-A1 | 3-(3-AMIDINOPHENYL)-5- ( 1-(1-(-IMINOETHYL)-4-PIPERIDYL AMINO)METHYL]BENZOIC ACID DIHYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME | TEIJIN LIMITED (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-20030203935-A1 | Cyanobiphenyl derivatives | TEIJIN LIMITED | 2003-10-30 | — | — | US | disclosed |
| US-6538137-B1 | Blood-coagulation factor X inhibitors | TEIJIN LIMITED (JP) | 2003-03-25 | — | — | US | disclosed |
| WO-2002060873-A1 | 3-(3-AMIDINOPHENYL)-5-[({[1-(1-(-IMINOETHYL)-4-PIPERIDYL}AMINO)METHYL]BENZOIC ACID DIHYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME | TEIJIN LIMITED (JP) | 2002-08-08 | — | — | WO | disclosed |
| EP-1179527-A1 | CYANOBIPHENYL DERIVATIVES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053967-A1 | 3-(3-Amidinophenyl)-5-[({[1-(1-(iminoethyl)-4-piperidyl}amino)methyl]benzoic acid dihydrochloride and process for preparing the same | AZI2, ACMSD, NPM1 | F10 497/4885F2 1326/4885PRSS1 3876/4885 |
| US-20030203935-A1 | Cyanobiphenyl derivatives | F9, F12, F11 | F10 7/4885F2 4/4885PRSS1 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.