Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130358 | 0.86 | SYK (0.48) | CA12CA1CA7CA14DPP9 | |
| SCHEMBL6887697 | 0.79 | AKT1 (0.43) | CA12CA1CA7CA14DPP9 | |
| SCHEMBL27231928 | 0.79 | SYK (0.53) | CA12CA1CA7CA14DPP9 | |
| SCHEMBL14657570 | 0.77 | MEN1 (0.42) | DPP9DPP8KMT2ALMNAGAA | |
| SCHEMBL26633304 | 0.74 | DPP8 (0.47) | CA12CA1CA7CA14DPP9 | |
| SCHEMBL29408962 | 0.74 | CA12 (0.46) | CA12CA1CA7CA14DPP9 | |
| SCHEMBL30561275 | 0.73 | GAA (0.40) | DPP9DPP8KMT2AALDH1A1LMNA | |
| SCHEMBL23460475 | 0.73 | SYK (0.47) | CA12CA1CA7CA14DPP9 | |
| Hydrochloric Acid SCHEMBL29495505 | 0.73 | CA12 (0.46) | CA12CA1CA7CA14DPP9 | |
| SCHEMBL21238259 | 0.72 | DPP8 (0.43) | CA12CA1CA7CA14DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389181-A4 | ANTIOXIDANT NITROXIDES AND NITRONES AS THERAPEUTIC AGENTS | PANORAMA RES INC (US) | 2005-10-19 | — | — | EP | disclosed |
| US-6852889-B2 | Antioxidant nitroxides and nitrones as therapeutic agents | PANORAMA RESEARCH, INC. (US) | 2005-02-08 | — | — | US | disclosed |
| US-6717012-B2 | SUCH AS ALPHA-PHENYL-N-(7-TERT-BUTOXYCARBONYLAMINO-3,5-DIMETHYLADAMANTANE)NITRONE FOR TREATMENT OF NEUROLOGICAL/ INFLAMMATORY DIORDERS, AND AGING, WHICH RESULT FROM THE OVERPRODUCTION OF NITRIC OXIDE | NEUROMOLECULAR, INC. | 2004-04-06 | — | — | US | disclosed |
| EP-1389181-A2 | ANTIOXIDANT NITROXIDES AND NITRONES AS THERAPEUTIC AGENTS | PANORAMA RESEARCH, INC. (US) | 2004-02-18 | — | — | EP | disclosed |
| US-20030045574-A1 | Antioxidant nitroxides and nitrones as therapeutic agents | PANORAMA RESEARCH, INC. | 2003-03-06 | — | — | US | disclosed |
| WO-2002078615-A2 | ANTIOXIDANT NITROXIDES AND NITRONES AS THERAPEUTIC AGENTS | PANORAMA RESEARCH, INC. (US) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045574-A1 | Antioxidant nitroxides and nitrones as therapeutic agents | NOS3, NOX3, NOX1 | CA12 2428/4885CA1 871/4885CA7 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.