Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130356 | 0.79 | CA12 (0.46) | AKT1CTSSDPP8DPP9CA12 | |
| SCHEMBL6130358 | 0.79 | SYK (0.48) | CTSSCTSLCTSBDPP8DPP9 | |
| SCHEMBL14657570 | 0.73 | MEN1 (0.42) | DPP8DPP9KMT2ANPSR1 | |
| SCHEMBL27231928 | 0.72 | SYK (0.53) | AKT1CTSSCTSLCTSBDPP8 | |
| SCHEMBL29584836 | 0.70 | CTSS (0.47) | AKT1CTSSCTSLCTSBDPP8 | |
| SCHEMBL30561275 | 0.69 | GAA (0.40) | DPP8DPP9KMT2ANPSR1 | |
| SCHEMBL23460475 | 0.69 | SYK (0.47) | AKT1CTSSCTSLDPP8DPP9 | |
| SCHEMBL21238259 | 0.69 | DPP8 (0.43) | AKT1CTSSDPP8DPP9CA12 | |
| SCHEMBL31628509 | 0.68 | NPFFR1 (0.49) | KMT2AL3MBTL1NPFFR1NPFFR2NPSR1 | |
| SCHEMBL19742775 | 0.68 | AKT1 (0.50) | AKT1CTSSCTSLCTSBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186320-A1 | Alpha-phenyl-N-(7-tert-butoxycarbonylamino-3,5-dialkyl -adamantane)nitrones; treating disorders resulting from overproduction of nitric oxide and other free radicals such as neurological, neuropsychiatric and inflammatory disorders | WANG YUQIANG (US) | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186320-A1 | Alpha-phenyl-N-(7-tert-butoxycarbonylamino-3,5-dialkyl -adamantane)nitrones; treating disorders resulting from overproduction of nitric oxide and other free radicals such as neurological, neuropsychiatric and inflammatory disorders | NOS1, NOS3, NOS2 | AKT1 1729/4885CTSS 1442/4885CTSL 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.