Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 10/20 | 0.41 |
| ▸ | NOS1 | P29475 | 7/20 | 0.41 |
| ▸ | NOS3 | P29474 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147730 | 0.86 | ARG1 (0.36) | NOS2NOS1NOS3CYP1A2ARG1 | |
| SCHEMBL16950254 | 0.83 | NOS2 (0.39) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL25455637 | 0.83 | NOS2 (0.39) | NOS2NOS1NOS3ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL9639751 | 0.81 | NOS2 (0.38) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL18130248 | 0.80 | GRIK1 (0.41) | NOS2NOS1NOS3ARG1ARG2 | |
| N-Monoacetylcystine SCHEMBL20816351 | 0.79 | MAPT (0.48) | NOS2NOS1NOS3MEN1CYP2C19 | |
| N-Monoacetylcystine SCHEMBL468824 | 0.79 | MAPT (0.48) | NOS2NOS1NOS3MEN1CYP2C19 | |
| N-Monoacetylcystine SCHEMBL111494 | 0.79 | MAPT (0.48) | NOS2NOS1NOS3MEN1CYP2C19 | |
| N-Monoacetylcystine SCHEMBL468826 | 0.79 | MAPT (0.48) | NOS2NOS1NOS3MEN1CYP2C19 | |
| N-Monoacetylcystine SCHEMBL29438781 | 0.79 | MAPT (0.48) | NOS2NOS1NOS3MEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429712-A4 | METHOD FOR TREATING BRONCHIAL CONSTRICTION AND BRONCHOSPASM | CELLULAR SCIENCES INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1429712-A2 | METHOD FOR TREATING BRONCHIAL CONSTRICTION AND BRONCHOSPASM | Cellular Sciences, Inc. (US) | 2004-06-23 | — | — | EP | disclosed |
| US-6623723-B2 | Method for treating bronchial constriction and bronchospasm | CELLULAR SCIENCES INC. | 2003-09-23 | — | — | US | disclosed |
| WO-2003017929-A2 | METHOD FOR TREATING BRONCHIAL CONSTRICTION AND BRONCHOSPASM | CELLULAR SCIENCES, INC. (US) | 2003-03-06 | — | — | WO | disclosed |
| US-20030039615-A1 | Method for treating bronchial constriction and bronchospasm | CELLUAR SCIENCES, INC. | 2003-02-27 | — | — | US | disclosed |