Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130508 | 0.86 | NOS2 (0.41) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL25455637 | 0.82 | NOS2 (0.39) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL16950254 | 0.82 | NOS2 (0.39) | ARG1ARG2NOS2NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL9639751 | 0.81 | NOS2 (0.38) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL11313177 | 0.79 | ARG1 (0.39) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL13066795 | 0.79 | GGT1 (0.36) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL2990974 | 0.78 | GLUL (0.37) | BHMT | |
| SCHEMBL2990989 | 0.78 | GLUL (0.37) | BHMT | |
| Cystine SCHEMBL8332353 | 0.78 | PTGS1 (0.50) | ARG1ARG2NOS2NOS1NOS3 | |
| Cystine SCHEMBL21114356 | 0.78 | PTGS1 (0.50) | ARG1ARG2NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797424-B1 | PROCESS FOR ENCAPSULATION OF CAPLETS IN A CAPSULE AND SOLID DOSAGE FORMS OBTAINABLE BY SUCH PROCESS | WARNER LAMBERT CO (US) | 2000-07-12 | — | — | EP | claimed |
| EP-2021093-B1 | A METHOD FOR GENERATING METAL CHELATING AFFINITY LIGANDS | GE HEALTHCARE BIO SCIENCES AB (SE) | 2011-12-21 | — | — | EP | disclosed |
| EP-1597269-B1 | A METHOD OF GENERATING METAL CHELATING AFFINITY LIGANDS | GE HEALTHCARE BIO SCIENCES AB (SE) | 2010-02-17 | — | — | EP | disclosed |
| EP-2021093-A1 | A METHOD FOR GENERATING METAL CHELATING AFFINITY LIGANDS | GE Healthcare Bio-Sciences AB (SE) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007137752-A1 | A METHOD FOR GENERATING METAL CHELATING AFFINITY LIGANDS | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2007-12-06 | — | — | WO | disclosed |
| US-7005071-B2 | Method of generating metal chelating affinity ligands | AMERSHAM BIOSCIENCES AB (SE) | 2006-02-28 | — | — | US | disclosed |
| US-20060027501-A1 | Method of generating metal chelating affinity ligands | AMERSHAM BIOSCIENCES AB | 2006-02-09 | — | — | US | disclosed |
| EP-1156802-B1 | PHARMACEUTIC, DIETETIC AND COSMETIC COMPOSITIONS BASED ON THIOCTIC ACID AND CYSTEINE | UNI CI S R L (IT) | 2005-12-07 | — | — | EP | disclosed |
| EP-1597269-A1 | A METHOD OF GENERATING METAL CHELATING AFFINITY LIGANDS | Amersham Biosciences AB (SE) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004087284-A1 | PREPARATION OF A METAL CHELATING SEPARATION MEDIUM | AMERSHAM BIOSCIENCES AB (SE) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004076475-A1 | A METHOD OF GENERATING METAL CHELATING AFFINITY LIGANDS | AMERSHAM BIOSCIENCES AB (SE) | 2004-09-10 | — | — | WO | disclosed |
| US-20040168983-A1 | Method of generating metal chelating affinity ligands | CYTIVA BIOPROCESS R&D AB (SE) | 2004-09-02 | — | — | US | disclosed |
| EP-1276716-A2 | METAL CHELATING COMPOSITIONS | Sigma-Aldrich Company (US) | 2003-01-22 | — | — | EP | disclosed |
| EP-1156802-A1 | PHARMACEUTIC, DIETETIC AND COSMETIC COMPOSITIONS BASED ON THIOCTIC ACID AND CYSTEINE | Uni-CI S.r.l (IT) | 2001-11-28 | — | — | EP | disclosed |
| WO-2001081365-A2 | METAL CHELATING COMPOSITIONS | SIGMA-ALDRICH CO. (US) | 2001-11-01 | — | — | WO | disclosed |
| WO-2000053176-A1 | PHARMACEUTIC, DIETETIC AND COSMETIC COMPOSITIONS BASED ON THIOCTIC ACID AND CYSTEINE | UNI-CI S.R.L. (IT) | 2000-09-14 | — | — | WO | disclosed |
| US-4340591-A | Process for obtention of the ovomucoid fraction and an ovomucoid extract of quail egg, products so obtained and their use as a medicament | SOCIETE COTURNIX (FR) | 1982-07-20 | — | — | US | disclosed |