SCHEMBL6130554

SCHEMBL6130554

OC(=COC=C(O)C1CCCCC1)C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
MGLL Q99685 1/20 0.33
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5987117 0.72 CES2 (0.41) CES2CES1MGLLHDAC8HDAC6
SCHEMBL27352218 0.72 CES2 (0.41) CES2CES1MGLLHDAC8HDAC6
SCHEMBL9656002 0.72 CES2 (0.36) CES2CES1MGLLHDAC8HDAC6
SCHEMBL18597012 0.69
SCHEMBL7919284 0.69 CES2 (0.33) CES2CES1MGLLALDH1A1TSHR
SCHEMBL8662238 0.67 CES2 (0.32) CES2CES1
SCHEMBL8209830 0.67 CES2 (0.48) CES2CES1HDAC8HDAC6ALDH1A1
SCHEMBL28780293 0.65
SCHEMBL18602303 0.65 CES2 (0.35) CES2CES1MGLLHDAC8HDAC6
SCHEMBL16976843 0.65 CES2 (0.46) CES2CES1HDAC8HDAC6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2601229-B1 GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS AMYRIS INC (US) 2013-10-16 EP claimed
WO-2022138768-A1 METHOD FOR PRODUCING FLUOROPOLYMER ダイキン工業株式会社 2022-06-30 WO disclosed
EP-1427694-A4 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM HONEYWELL INT INC (US) 2005-06-22 EP disclosed
EP-1451235-A4 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM HONEYWELL INT INC (US) 2005-06-22 EP disclosed
US-6809216-B2 WATERPROOFING, OIL REPELLENTS, ANTISOILANTS HONEYWELL INTERNATIONAL INC. 2004-10-26 US disclosed
US-6800788-B2 FLUORINE-CONTAINING COMPOUNDS, AND POLYMERS DERIVED THEREFROM, FOR USE IN COMPOSITIONS USED FOR TREATING TEXTILE SUBSTRATES. ALSO PROVIDED ARE METHODS OF MAKING FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM, COMPOSITIONS HONEYWELL INTERNATIONAL INC. 2004-10-05 US disclosed
EP-1451235-A2 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM Honeywell International Inc. (US) 2004-09-01 EP disclosed
EP-1451228-A1 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM Honeywell International, Inc. (US) 2004-09-01 EP disclosed
EP-1427694-A1 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM Honeywell International Inc. (US) 2004-06-16 EP disclosed
US-20030109626-A1 Fluorine-containing compounds and polymers derived therefrom HONEYWELL INTERNATIONAL INC. 2003-06-12 US disclosed
US-20030092828-A1 Fluorine-containing compounds and polymers derived therefrom BRADLEY DAVID E (US) 2003-05-15 US disclosed
US-20030039919-A1 Fluorine-containing compounds and polymers derived therefrom HONEYWELL INTERNATIONAL INC. 2003-02-27 US disclosed
WO-2002103103-A2 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM HONEYWELL INTERNATIONAL INC. (US) 2002-12-27 WO disclosed
WO-2002102858-A1 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM HONEYWELL INTERNATIONAL, INC. (US) 2002-12-27 WO disclosed
WO-2002102758-A1 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM HONEYWELL INTERNATIONAL, INC. (US) 2002-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109626-A1 Fluorine-containing compounds and polymers derived therefrom WASF2, NOTUM, NEFM CES2 180/4885CES1 1444/4885MGLL 1140/4885
US-20030092828-A1 Fluorine-containing compounds and polymers derived therefrom WASF2, NOTUM, PFAS CES2 154/4885CES1 1325/4885MGLL 1297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.