Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.63 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130888 | 0.91 | ELANE (0.61) | ELANEPRTN3ATMECE1MME | |
| SCHEMBL5076528 | 0.86 | ELANE (0.67) | ELANEPRTN3ATMECE1MME | |
| SCHEMBL2353877 | 0.84 | ELANE (0.72) | ELANEPRTN3ATMECE1MME | |
| SCHEMBL2353879 | 0.84 | ELANE (0.72) | ELANEPRTN3ATMECE1MME | |
| SCHEMBL6130897 | 0.79 | ELANE (0.44) | ELANEPRTN3ECE1MMEACE2 | |
| SCHEMBL9970972 | 0.78 | ELANE (1.00) | ELANEPRTN3 | |
| SCHEMBL4163321 | 0.76 | ELANE (0.60) | ELANEPRTN3ATMECE1MME | |
| SCHEMBL8740045 | 0.76 | ELANE (0.60) | ELANEPRTN3ATMECE1MME | |
| SCHEMBL11567174 | 0.76 | ELANE (0.60) | ELANEPRTN3ATMECE1MME | |
| SCHEMBL5073962 | 0.76 | ELANE (0.54) | ELANEPRTN3ECE1MMEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497300-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | Schering Aktiengesellschaft (DE) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003080631-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |