Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.61 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.57 |
| ▸ | KYNU | Q16719 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130869 | 0.91 | ELANE (0.63) | ELANEPRTN3ATMECE1MME | |
| SCHEMBL5076528 | 0.87 | ELANE (0.67) | ELANEPRTN3KYNUATMECE1 | |
| SCHEMBL2353879 | 0.82 | ELANE (0.72) | ELANEPRTN3KYNUATMECE1 | |
| SCHEMBL2353877 | 0.82 | ELANE (0.72) | ELANEPRTN3KYNUATMECE1 | |
| SCHEMBL6923368 | 0.76 | KYNU (0.57) | ELANEPRTN3KYNUATMECE1 | |
| SCHEMBL6923362 | 0.76 | KYNU (0.57) | ELANEPRTN3KYNUATMECE1 | |
| SCHEMBL2353547 | 0.76 | ELANE (0.60) | ELANEPRTN3KYNUECE1MME | |
| SCHEMBL9970972 | 0.76 | ELANE (1.00) | ELANEPRTN3KLK1 | |
| SCHEMBL9152554 | 0.75 | ELANE (0.62) | ELANEPRTN3KYNUATMECE1 | |
| SCHEMBL9152551 | 0.75 | ELANE (0.62) | ELANEPRTN3KYNUATMECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497300-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | Schering Aktiengesellschaft (DE) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003080631-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |