Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 1.00 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.76 |
| ▸ | KLK1 | P06870 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | PLAU | P00749 | 7/20 | 0.60 |
| ▸ | F2 | P00734 | 6/20 | 0.60 |
| ▸ | PLAT | P00750 | 6/20 | 0.60 |
| ▸ | PLG | P00747 | 6/20 | 0.56 |
| ▸ | KLK8 | O60259 | 5/20 | 0.56 |
| ▸ | KLK4 | Q9Y5K2 | 5/20 | 0.56 |
| ▸ | F10 | P00742 | 4/20 | 0.56 |
| ▸ | KLK2 | P20151 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689257 | 0.87 | ELANE (0.77) | ELANEPRTN3KLK1TP53PLAU | |
| SCHEMBL2353877 | 0.84 | ELANE (0.72) | ELANEPRTN3 | |
| SCHEMBL2353879 | 0.84 | ELANE (0.72) | ELANEPRTN3 | |
| SCHEMBL5881673 | 0.82 | ELANE (0.70) | ELANEPRTN3KLK1TP53PLAU | |
| SCHEMBL7403534 | 0.81 | F2 (0.86) | ELANEPRTN3KLK1TP53PLAU | |
| SCHEMBL5076528 | 0.81 | ELANE (0.67) | ELANEPRTN3 | |
| SCHEMBL9970954 | 0.80 | PRTN3 (0.79) | ELANEPRTN3KLK1TP53PLAU | |
| SCHEMBL1436662 | 0.80 | ELANE (0.66) | ELANEPRTN3KLK1TP53PLAU | |
| SCHEMBL6130869 | 0.78 | ELANE (0.63) | ELANEPRTN3 | |
| SCHEMBL9152554 | 0.77 | ELANE (0.62) | ELANEPRTN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470672-B1 | COMPOUNDS FOR DETECTING PROTEASES | UNIV BELFAST (GB) | 2016-10-12 | — | — | EP | disclosed |
| US-9340820-B2 | Compounds and methods for protease detection | QUEEN'S UNIVERSITY OF BELFAST (GB) | 2016-05-17 | — | — | US | disclosed |
| US-20120156691-A1 | COMPOUND | QUEEN'S UNIVERSITY OF BELFAST | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120156691-A1 | COMPOUND | DNPEP, TMPRSS15, PEPD | ELANE 51/4885PRTN3 140/4885KLK1 469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.