Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130860 | 0.76 | HPGD (0.47) | HPGDALOX15RAB9ALMNAMEN1 | |
| SCHEMBL2349796 | 0.76 | IDO1 (0.46) | PPARGMEN1KMT2A | |
| SCHEMBL4607143 | 0.76 | PDK1 (0.49) | RAB9ALMNAMEN1KMT2AMAPK1 | |
| SCHEMBL6130848 | 0.74 | RAB9A (0.48) | HPGDRAB9ALMNAMEN1KMT2A | |
| SCHEMBL9813603 | 0.73 | KDM4E (0.52) | KDM4EHPGDALOX15RAB9ALMNA | |
| SCHEMBL3682275 | 0.72 | KMT2A (0.53) | LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL2853118 | 0.68 | KMT2A (0.44) | KDM4ERAB9ALMNAMEN1KMT2A | |
| SCHEMBL10573282 | 0.68 | MEN1 (0.50) | KDM4EHPGDALOX15RAB9ALMNA | |
| SCHEMBL14986223 | 0.68 | HPGD (0.61) | KDM4EHPGDALOX15RAB9ALMNA | |
| SCHEMBL698273 | 0.68 | HPGD (0.47) | KDM4EHPGDALOX15RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497300-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | Schering Aktiengesellschaft (DE) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003080631-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |