SCHEMBL6131243

SCHEMBL6131243

c1ccc(Nc2ccc3ncsc3c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.56
KDR P35968 7/20 0.52
INSR P06213 4/20 0.52
TEK Q02763 4/20 0.52
PDGFRB P09619 3/20 0.52
PDGFRA P16234 3/20 0.52
IKBKB O14920 3/20 0.52
CSF1R P07333 2/20 0.52
TGFBR1 P36897 1/20 0.51
DYRK3 O43781 1/20 0.50
CLK1 P49759 1/20 0.50
CLK2 P49760 1/20 0.50
CLK3 P49761 1/20 0.50
GSK3B P49841 1/20 0.50
DYRK1A Q13627 1/20 0.50
DYRK2 Q92630 1/20 0.50
CLK4 Q9HAZ1 1/20 0.50
DYRK4 Q9NR20 1/20 0.50
DYRK1B Q9Y463 1/20 0.50
PRKD1 Q15139 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24588180 0.86 RIPK2 (0.56) KDRTGFBR1ALDH1A1HSD17B10TDP1
SCHEMBL6395906 0.84 KDR (0.60) SYKKDRINSRTEKPDGFRB
Diphenylamine SCHEMBL15048582 0.84 HSD17B10 (0.73) SYKKDRINSRTEKPDGFRB
SCHEMBL17801752 0.81 SYK (0.69) SYKKDRINSRTEKPDGFRB
SCHEMBL2229449 0.81 TGFBR1 (0.56) SYKKDRINSRTEKPDGFRB
SCHEMBL28411768 0.81 RIPK1 (0.48) SYKKDRINSRTEKPDGFRB
SCHEMBL28411629 0.81 NPC1 (0.62) SYKKDRINSRTEKPDGFRB
SCHEMBL20311432 0.80 SYK (0.49) SYKKDRINSRTEKPDGFRB
SCHEMBL28411750 0.79 MEN1 (0.50) SYKKDRINSRTEKPDGFRB
SCHEMBL24904477 0.78 KDR (0.62) SYKKDRINSRTEKPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111153872-A Dithio-dibenzothiazole compound and preparation method and application thereof 江苏方圆芳纶研究院有限公司 2020-05-15 CN claimed
US-11812657-B2 Organic electric element DUK SAN NEOLUX CO., LTD. 2023-11-07 US disclosed
US-11812657-B2 Organic electric element DUK SAN NEOLUX CO., LTD. 2023-11-07 US disclosed
US-20230276699-A1 Organic Electric Element DUK SAN NEOLUX CO LTD (KR) 2023-08-31 US disclosed
US-20230276699-A1 Organic Electric Element DUK SAN NEOLUX CO LTD (KR) 2023-08-31 US disclosed
US-20220209127-A1 ORGANIC ELECTRIC ELEMENT DUK SAN NEOLUX CO., LTD (KR) 2022-06-30 US disclosed
CN-111153872-A Dithio-dibenzothiazole compound and preparation method and application thereof 江苏方圆芳纶研究院有限公司 2020-05-15 CN disclosed
US-6878510-B2 Method of processing silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-04-12 US disclosed
US-20050032008-A1 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. 2005-02-10 US disclosed
US-6844146-B2 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-01-18 US disclosed
US-20040058282-A1 Method of processing silver halide photosensitive material FUJI PHOTO FILM CO., LTD. 2004-03-25 US disclosed
US-6696215-B2 HIGH CONTRAST AND PHOTOSENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 2004-02-24 US disclosed
US-20040018458-A1 Photothermographic material FUJIFILM CORPORATION (JP) 2004-01-29 US disclosed
US-20030232272-A1 Silver halide photographic light sensitive material FUJIFILM CORPORATION (JP) 2003-12-18 US disclosed
US-20030198905-A1 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. 2003-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276699-A1 Organic Electric Element EPCAM, ESR1, SOD1 SYK 2798/4885KDR 1702/4885INSR 3694/4885
US-20220209127-A1 ORGANIC ELECTRIC ELEMENT EPCAM, ESR1, SOD1 SYK 2798/4885KDR 1702/4885INSR 3694/4885
US-11812657-B2 Organic electric element EPCAM, ESR1, SOD1 SYK 2798/4885KDR 1702/4885INSR 3694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.