SCHEMBL6131275

SCHEMBL6131275

Sc1ccc2c(c1)CCCN2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
KDM4E B2RXH2 2/20 0.54
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
GAA P10253 2/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 1/20 0.50
THRB P10828 1/20 0.50
ALOX15 P16050 1/20 0.50
CASP1 P29466 1/20 0.50
HTT P42858 1/20 0.50
CASP7 P55210 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
HRH3 Q9Y5N1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3365351 0.88 DRD2 (0.59) MAPTKDM4ECA12CA1CA2
SCHEMBL12821127 0.84 HRH3 (0.42) MAPTKDM4ECA12CA1CA2
SCHEMBL29722558 0.76 DRD2 (0.78) MAPTKDM4ECA12CA1CA2
SCHEMBL5539388 0.76 MAPT (0.54) MAPTKDM4ECA12CA1CA2
SCHEMBL531817 0.76 MAPT (0.54) MAPTKDM4ECA12CA1CA2
SCHEMBL532839 0.76 DRD2 (0.78) MAPTKDM4ECA12CA1CA2
SCHEMBL566283 0.76 MAPT (0.54) MAPTKDM4ECA12CA1CA2
SCHEMBL379224 0.76 CA9 (0.57) MAPTKDM4ECA12CA1CA2
SCHEMBL1556861 0.76 MAPT (0.54) MAPTKDM4ECA12CA1CA2
SCHEMBL1091532 0.76 MAPT (0.54) MAPTKDM4ECA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6878510-B2 Method of processing silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-04-12 US disclosed
US-20050032008-A1 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. 2005-02-10 US disclosed
US-6844146-B2 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-01-18 US disclosed
US-20040058282-A1 Method of processing silver halide photosensitive material FUJI PHOTO FILM CO., LTD. 2004-03-25 US disclosed
US-6696215-B2 HIGH CONTRAST AND PHOTOSENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 2004-02-24 US disclosed
US-20040018458-A1 Photothermographic material FUJIFILM CORPORATION (JP) 2004-01-29 US disclosed
US-20030232272-A1 Silver halide photographic light sensitive material FUJIFILM CORPORATION (JP) 2003-12-18 US disclosed
US-20030198905-A1 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. 2003-10-23 US disclosed
CN-1052002-C Ether derivatives of tetrahydropyran and tetrahydrofuran, process for their preparation and pharmaceutical compositions containing them ZENECA LTD (GB) 2000-05-03 CN disclosed