Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.78 |
| ▸ | DRD4 | P21917 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29722558 | 1.00 | DRD2 (0.78) | DRD2DRD4MAPTKDM4ECA12 | |
| SCHEMBL6247150 | 0.94 | DRD2 (0.75) | DRD2DRD4MAPTKDM4ECA12 | |
| Bromide SCHEMBL3182004 | 0.92 | DRD2 (0.72) | DRD2DRD4MAPTKDM4ECA12 | |
| SCHEMBL59263 | 0.88 | DRD2 (1.00) | DRD2DRD4MAPTKDM4ECA12 | |
| Hydrochloric Acid SCHEMBL3900412 | 0.86 | DRD2 (0.96) | DRD2DRD4MAPTKDM4ECA12 | |
| SCHEMBL1119368 | 0.84 | DRD2 (0.55) | DRD2DRD4MAPTKDM4ECA12 | |
| Tert-Butyl Formate SCHEMBL27510897 | 0.82 | DRD2 (0.54) | DRD2DRD4MAPTKDM4ECA12 | |
| SCHEMBL6712764 | 0.81 | DRD2 (0.85) | DRD2DRD4MAPTKDM4ECA12 | |
| SCHEMBL1091532 | 0.80 | MAPT (0.54) | DRD2DRD4MAPTKDM4ECA12 | |
| SCHEMBL6807924 | 0.78 | DRD2 (0.53) | DRD2DRD4MAPTKDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119931978-A | Application of monoamine oxidase as catalyst in preparation of quinoline nitrogen heterocyclic compound | 河北工业大学 | 2025-05-06 | — | — | CN | claimed |
| CN-117986187-A | Compound and acrylamide polymer with oil displacement effect as well as preparation methods and applications thereof | 中国石油化工股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-115626889-B | Organic chemical conversion method for oxidative dehydrogenation of nitrogen-containing heterocyclic compound | 南京工业大学 | 2024-04-30 | — | — | CN | claimed |
| CN-116376858-A | Application of monoamine oxidase from microorganism as catalyst in preparation of quinoline or quinoline derivative | 浙江大学杭州国际科创中心 | 2023-07-04 | — | — | CN | claimed |
| CN-103524409-B | Quinolines and preparation method thereof and application | Shanghai Ren Li Pharmaceutical Technology Co., Ltd (CN) | 2015-09-02 | — | — | CN | claimed |
| CN-103509005-B | Quinazoline compound as well as preparation method and application thereof | SUZHOU HAITE BIAO BIOLOG TECHNOLOGY CO LTD | 2015-04-08 | — | — | CN | claimed |
| US-7101869-B2 | 2,4-diaminopyrimidine compounds useful as immunosuppressants | PFIZER INC. (US) | 2006-09-05 | — | — | US | claimed |
| EP-1242403-B1 | 2,4-DIAMINOPYRIMIDINE COMPOUNDS USFUL AS IMMUNOSUPPRESSANTS | PFIZER PROD INC (US) | 2006-01-04 | — | — | EP | claimed |
| US-20030191307-A1 | 2,4-Diaminopyrimidine compounds useful as immunosuppressants | BLUMENKOPF TODD A (US) | 2003-10-09 | — | — | US | claimed |
| EP-1242403-A1 | 2,4-DIAMINOPYRIMIDINE COMPOUNDS USFUL AS IMMUNOSUPPRESSANTS | Pfizer Products Inc. (US) | 2002-09-25 | — | — | EP | claimed |
| WO-2001040215-A1 | 2,4-DIAMINOPYRIMIDINE COMPOUNDS USFUL AS IMMUNOSUPPRESSANTS | PFIZER PRODUCTS INC. (US) | 2001-06-07 | — | — | WO | claimed |
| EP-0103797-B1 | SUBSTITUTED BENZOXAZINE DERIVATIVES | BAYER AG (DE) | 1986-11-26 | — | — | EP | claimed |
| EP-0103797-A2 | Substituted benzoxazine derivatives | BAYER AG (DE) | 1984-03-28 | — | — | EP | claimed |
| US-12624044-B2 | SMARCA degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| US-12551564-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2026-02-17 | — | — | US | disclosed |
| CN-121108623-B | EVA (ethylene-vinyl acetate copolymer) chemical foaming sole material with high whiteness and preparation method thereof | 安踏（中国）有限公司 | 2026-02-03 | — | — | CN | disclosed |
| US-4088793-A | NITROXIDE DERIVATIVES OF 1,2-DIHYDRO- AND 1,2,3,4-TETRAHYDRO- 6-ALKOXYQUINOLINES | CANADA PACKERS LIMITED (CA) | 1978-05-09 | — | — | US | disclosed |
| US-4055428-A | COLO PHOTOGRAPHY, DIFFUSION TRANSFER SILVER HALIDE EMULSIONS | FUJI PHOTO FILM CO., LTD. (JA) | 1977-10-25 | — | — | US | disclosed |
| US-3997542-A | 1-(Halogenated-acetyl)-1,2,3,4-tetrahydro-6-quinolinols and esters thereof | STERLING DRUG INC. (US) | 1976-12-14 | — | — | US | disclosed |
| US-3997542-A | 1-(Halogenated-acetyl)-1,2,3,4-tetrahydro-6-quinolinols and esters thereof | STERLING DRUG INC. (US) | 1976-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191307-A1 | 2,4-Diaminopyrimidine compounds useful as immunosuppressants | CCR1, AOC1, NOD1 | DRD2 1796/4885DRD4 1511/4885MAPT 4588/4885 |
| US-12551564-B2 | IRAK degraders and uses thereof | IRAK2, IRAK3, IRAK1 | DRD2 1474/4885DRD4 2946/4885MAPT 4432/4885 |
| US-12624044-B2 | SMARCA degraders and uses thereof | SMARCA1, SMARCC1, SMARCA2 | DRD2 3826/4885DRD4 4069/4885MAPT 2169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.