Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28337783 | 0.98 | CA9 (0.56) | CA9CA12CA1CA2MAPT | |
| SCHEMBL2616928 | 0.94 | CA9 (0.51) | CA9CA12CA1CA2MAPT | |
| SCHEMBL1880170 | 0.88 | DRD2 (0.59) | CA9CA12CA1CA2MAPT | |
| SCHEMBL29642933 | 0.88 | DRD2 (0.59) | CA9CA12CA1CA2MAPT | |
| Hydrochloric Acid SCHEMBL3870202 | 0.86 | DRD2 (0.57) | CA9CA12CA1CA2MAPT | |
| Hydrochloric Acid SCHEMBL3565219 | 0.86 | DRD2 (0.57) | CA9CA12CA1CA2MAPT | |
| SCHEMBL29522368 | 0.84 | MAPT (0.50) | CA9CA12CA1CA2MAPT | |
| SCHEMBL1098919 | 0.84 | MAPT (0.50) | CA9CA12CA1CA2MAPT | |
| Hydrochloric Acid SCHEMBL19743521 | 0.82 | MAPT (0.49) | CA9CA12CA1CA2MAPT | |
| Hydrochloric Acid SCHEMBL29566172 | 0.82 | MAPT (0.49) | CA9CA12CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602829-A | Cxcr4 receptor antagonists | 百时美施贵宝公司 | 2018-09-28 | — | — | CN | claimed |
| CN-103827105-A | Substituted heterocyclic amine compounds as cholestryl ester-transfer protein (CETP) inhibitors | REDDYS LAB LTD DR | 2014-05-28 | — | — | CN | claimed |
| EP-0670312-A1 | Color developing agent, processing composition and color image-forming method | Fuji Photo Film Co., Ltd. (JP) | 1995-09-06 | — | — | EP | claimed |
| WO-1994028863-A1 | 8-AMINO-1,2,3,4-TETRAHYDROQUINOLINES AS COUPLERS IN DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1994-12-22 | — | — | WO | claimed |
| US-20230192643-A1 | DIHYDROQUINOLINONES FOR MEDICAL TREATMENT | C4 THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-11401256-B2 | Dihydroquinolinones for medical treatment | C4 THERAPEUTICS, INC. (US) | 2022-08-02 | — | — | US | disclosed |
| WO-2021183431-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-16 | — | — | WO | disclosed |
| CN-112225696-A | Method for preparing quinoline derivative by catalyzing nitrogen heterocycle dehydrogenation through manganese oxide | 河南省化工研究所有限责任公司 | 2021-01-15 | — | — | CN | disclosed |
| US-10752624-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2020-08-25 | — | — | US | disclosed |
| US-10745364-B2 | Tetrahydronaphthyridine, benzoxazine, aza-benzoxazine and related bicyclic compounds for inhibition of RORgamma activity and the treatment of disease | LYCERA CORPORATION (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190292159-A1 | TETRAHYDRONAPHTHYRIDINE, BENZOXAZINE, AZA-BENZOXAZINE AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE | MERCK SHARP & DOHME LLC | 2019-09-26 | — | — | US | disclosed |
| EP-3474814-A1 | USE FOR DYEING KERATIN FIBERS OF A COMPOUND OF AZOMETHINE TYPE BEARING A QUINOLINE-DERIVED UNIT | L'OREAL (FR) | 2019-05-01 | — | — | EP | disclosed |
| US-5962200-A | 6-AMINOTETRAHYDROQUINOLINE COLOR DEVELOPING COMPOUNDS OR ANALOGUES THEREOF. A RAPID PROCESS CAN BE ATTAINED. | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5962200-A | 6-AMINOTETRAHYDROQUINOLINE COLOR DEVELOPING COMPOUNDS OR ANALOGUES THEREOF. A RAPID PROCESS CAN BE ATTAINED. | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5721093-A | DEVELOPER IS A 7-AMINOINDOLE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1998-02-24 | — | — | US | disclosed |
| EP-0670312-A1 | Color developing agent, processing composition and color image-forming method | Fuji Photo Film Co., Ltd. (JP) | 1995-09-06 | — | — | EP | disclosed |
| EP-0670312-A1 | Color developing agent, processing composition and color image-forming method | Fuji Photo Film Co., Ltd. (JP) | 1995-09-06 | — | — | EP | disclosed |
| WO-1994028863-A1 | 8-AMINO-1,2,3,4-TETRAHYDROQUINOLINES AS COUPLERS IN DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1994-12-22 | — | — | WO | disclosed |
| WO-1994028863-A1 | 8-AMINO-1,2,3,4-TETRAHYDROQUINOLINES AS COUPLERS IN DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1994-12-22 | — | — | WO | disclosed |
| WO-1994028863-A1 | 8-AMINO-1,2,3,4-TETRAHYDROQUINOLINES AS COUPLERS IN DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1994-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745364-B2 | Tetrahydronaphthyridine, benzoxazine, aza-benzoxazine and related bicyclic compounds for inhibition of RORgamma activity and the treatment of disease | RORB, RORA, RORC | CA9 869/4885CA12 466/4885CA1 732/4885 |
| US-20230192643-A1 | DIHYDROQUINOLINONES FOR MEDICAL TREATMENT | CRBN, RBX1, ADRM1 | CA9 4311/4885CA12 3594/4885CA1 2644/4885 |
| US-20190292159-A1 | TETRAHYDRONAPHTHYRIDINE, BENZOXAZINE, AZA-BENZOXAZINE AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE | RORB, RORA, RORC | CA9 869/4885CA12 466/4885CA1 732/4885 |
| US-11401256-B2 | Dihydroquinolinones for medical treatment | CRBN, RBX1, ADRM1 | CA9 4311/4885CA12 3594/4885CA1 2644/4885 |
| US-10752624-B2 | Kinase inhibitors | LRRK2, MYLK2, MYLK | CA9 4678/4885CA12 4853/4885CA1 4820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.