Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.68 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | TLR3 | O15455 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KIT | P10721 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614498 | 0.82 | LIMK1 (0.67) | LIMK1LIMK2KDM4EMAPTNPSR1 | |
| SCHEMBL31061690 | 0.82 | LIMK1 (0.61) | LIMK1LIMK2KITDYRK1AGSK3A | |
| SCHEMBL614767 | 0.82 | LIMK1 (0.61) | LIMK1LIMK2KITDYRK1AGSK3A | |
| SCHEMBL612219 | 0.81 | LIMK1 (1.00) | LIMK1LIMK2KDM4EMAPTRAB9A | |
| SCHEMBL11077910 | 0.81 | STING1 (0.54) | LIMK1LIMK2KDM4EMAPTRAB9A | |
| SCHEMBL16009072 | 0.80 | ALDH1A1 (0.59) | KDM4EMAPTRAB9AMEN1KMT2A | |
| SCHEMBL1656578 | 0.80 | ALDH1A1 (0.59) | KDM4EMAPTRAB9AMEN1KMT2A | |
| SCHEMBL614782 | 0.78 | KDM4E (0.53) | LIMK1LIMK2KDM4EMAPTRAB9A | |
| SCHEMBL10547752 | 0.76 | DYRK1A (0.59) | KDM4EMAPTRAB9ARECQLMEN1 | |
| SCHEMBL9736132 | 0.75 | KDM4E (0.65) | KDM4EMAPTRAB9ARECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604048-B2 | Pyridocarbazole type compounds and applications thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-12-10 | — | — | US | disclosed |
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-16 | — | — | US | disclosed |
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-16 | — | — | US | disclosed |
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-16 | — | — | US | disclosed |
| WO-2010095042-A2 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | NLN, OPA1, PYCR1 | LIMK1 2270/4885LIMK2 2037/4885KDM4E 3884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.