Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | TLR3 | O15455 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656578 | 0.84 | ALDH1A1 (0.59) | STING1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL615545 | 0.82 | MAOA (0.53) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL613137 | 0.81 | LIMK1 (0.68) | STING1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL11081378 | 0.80 | NQO2 (0.51) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL612838 | 0.74 | KIT (0.59) | STING1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL614041 | 0.73 | KIT (0.58) | STING1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL9678106 | 0.73 | KIT (0.55) | STING1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL20138908 | 0.72 | DYRK1A (0.54) | KDM4EALDH1A1KMT2AHSD17B10DYRK1A | |
| SCHEMBL16009072 | 0.72 | ALDH1A1 (0.59) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8548801 | 0.72 | KIT (0.54) | STING1KDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434290-A | TREATMENT OF LEUKEMIAS | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (FR) | 1984-02-28 | — | — | US | disclosed |