Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131366 | 0.81 | CCR1 (0.46) | METAP2CCR1CCR5SLC40A1TDP1 | |
| SCHEMBL2115749 | 0.77 | CCR1 (0.64) | METAP2CCR1RAB9ACCR5PARP1 | |
| Hydrochloric Acid SCHEMBL6292374 | 0.72 | METAP2 (0.41) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL27509727 | 0.70 | METAP2 (0.46) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL27594921 | 0.69 | METAP2 (0.53) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL2116625 | 0.68 | METAP2 (0.52) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL12642227 | 0.66 | METAP2 (0.59) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL5110386 | 0.66 | METAP2 (0.53) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL25302893 | 0.66 | CRHR1 (0.51) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL806441 | 0.66 | CCR1 (0.64) | METAP2CCR1RAB9ACCR5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100354287-C | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten with donor bridge | BASSEL POLYOLEFIN AG (DE) | 2007-12-12 | — | — | CN | disclosed |
| US-6919412-B1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten with a donor bridge | BASELL POLYOLEFINE GMBH (DE) | 2005-07-19 | — | — | US | disclosed |
| EP-1288219-B1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten with a donor bridge | BASELL POLYOLEFINE GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6838563-B2 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | BASELL POLYOLEFINS (DE) | 2005-01-04 | — | — | US | disclosed |
| US-6787498-B2 | AS CATALYSTS FOR POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-09-07 | — | — | US | disclosed |
| US-6699948-B2 | AS CATALYSTS FOR POLYMERIZATION OF OLEFINS | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030055267-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | MIHAN SHAHRAM (DE) | 2003-03-20 | — | — | US | disclosed |
| EP-1288219-A2 | Monocyclopentadienyl complexes of chromium molybdenum or tungsten with a donor bridge | Basell Polyolefine GmbH (DE) | 2003-03-05 | — | — | EP | disclosed |
| CN-1399640-A | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten with donor bridge | BASSEL POLYOLEFIN AG (DE) | 2003-02-26 | — | — | CN | disclosed |
| US-20030036658-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | MIHAN SHAHRAM (DE) | 2003-02-20 | — | — | US | disclosed |
| US-20030036662-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | MIHAN SHAHRAM (DE) | 2003-02-20 | — | — | US | disclosed |
| EP-1212333-B1 | MONOCYCLOPENTADIENYL COMPLEXES OF CHROMIUM, MOLYBDENUM OR TUNGSTEN WITH A DONOR BRIDGE | BASELL POLYOLEFINE GMBH (DE) | 2003-02-12 | — | — | EP | disclosed |
| US-6437161-B1 | OLEFIN POLYMERIZATION CATALYSTS; SUBSTITUENT ON THE CYCLOPENTADIENYL RING CARRIES A DONOR FUNCTION WHICH IS BONDED RIGIDLY, NOT EXCLUSIVELY VIA SP3-HYBRIDIZED CARBON OR SILICON ATOMS, | BASF AKTIENGESELLSCHAFT (DE) | 2002-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055267-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | SKIC3, ORC3, MCM3 | METAP2 1806/4885CCR1 180/4885RAB9A 4818/4885 |
| US-20030036662-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | SKIC3, ORC3, MCM3 | METAP2 1806/4885CCR1 180/4885RAB9A 4818/4885 |
| US-20030036658-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | SKIC3, ORC3, MCM3 | METAP2 1806/4885CCR1 180/4885RAB9A 4818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.