SCHEMBL27509727

SCHEMBL27509727

CC1=C(Cl)C(C)=C(Cl)[C]1c1cccc2ccc(C)nc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.46
CCR1 P32246 1/20 0.44
RAB9A P51151 1/20 0.44
CCR5 P51681 1/20 0.44
PARP1 P09874 1/20 0.41
BDKRB2 P30411 1/20 0.39
GLO1 Q04760 2/20 0.39
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
NFKBIA P25963 1/20 0.36
RELA Q04206 1/20 0.36
TP53 P04637 1/20 0.36
LMNA P02545 1/20 0.36
SLC40A1 Q9NP59 2/20 0.35
AGTR1 P30556 1/20 0.35
PAX8 Q06710 1/20 0.35
CYP1A2 P05177 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2115749 0.78 CCR1 (0.64) METAP2CCR1RAB9ACCR5PARP1
SCHEMBL2757274 0.71 METAP2 (0.59) METAP2CCR1RAB9ACCR5PARP1
SCHEMBL6131372 0.70 METAP2 (0.45) METAP2CCR1RAB9ACCR5PARP1
SCHEMBL2116625 0.69 METAP2 (0.52) METAP2CCR1RAB9ACCR5PARP1
SCHEMBL12642227 0.67 METAP2 (0.59) METAP2CCR1RAB9ACCR5PARP1
SCHEMBL25302893 0.67 CRHR1 (0.51) METAP2CCR1RAB9ACCR5PARP1
SCHEMBL806441 0.67 CCR1 (0.64) METAP2CCR1RAB9ACCR5PARP1
8-Hydroxy Quinaldine SCHEMBL1714541 0.66 METAP2 (0.57) METAP2CCR1RAB9ACCR5PARP1
Neocuproine SCHEMBL11672280 0.65 CCR1 (1.00) METAP2CCR1RAB9ACCR5PARP1
Neocuproine SCHEMBL124563 0.65 CCR1 (1.00) METAP2CCR1RAB9ACCR5PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1255441-C Process for the polymerization of olefins BASELL POLYOLEFINE GMBH (DE) 2006-05-10 CN disclosed
CN-1553920-A Method of polymerization of olefins ��������ϩ���ɷ����޹�˾ 2004-12-08 CN disclosed