Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771406 | 0.87 | TSHR (0.59) | TSHRALDH1A1TRPA1GABRA1GABRB2 | |
| SCHEMBL282162 | 0.87 | TSHR (1.00) | TSHRALDH1A1TRPA1GABRA1GABRB2 | |
| SCHEMBL15485172 | 0.87 | TSHR (1.00) | TSHRALDH1A1TRPA1GABRA1GABRB2 | |
| SCHEMBL20721726 | 0.87 | TSHR (1.00) | TSHRALDH1A1TRPA1GABRA1GABRB2 | |
| Ammonia Solution, Strong SCHEMBL27764945 | 0.85 | TSHR (0.95) | TSHRALDH1A1GABRA1GABRB2HDAC4 | |
| SCHEMBL29178964 | 0.85 | TSHR (0.95) | TSHRALDH1A1GABRA1GABRB2HDAC4 | |
| Benzene SCHEMBL1836843 | 0.85 | TSHR (0.95) | TSHRALDH1A1TRPA1GABRA1GABRB2 | |
| SCHEMBL27887359 | 0.85 | TSHR (0.95) | TSHRALDH1A1GABRA1GABRB2HDAC4 | |
| Hydrochloric Acid SCHEMBL7075092 | 0.85 | TSHR (0.95) | TSHRALDH1A1GABRA1GABRB2HDAC4 | |
| Hydrochloric Acid SCHEMBL6040007 | 0.83 | TSHR (0.91) | TSHRALDH1A1GABRA1GABRB2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100584812-C | Process for manufacture of bisphenols | GEN ELECTRIC | 2010-01-27 | — | — | CN | disclosed |
| CN-1745053-A | Process for producing bisphenols | GEN ELECTRIC (US) | 2006-03-08 | — | — | CN | disclosed |
| US-6858759-B2 | Adding a combined stream of a feed stream and a recycle stream into a reactor system containing an acid catalyst, wherein the combined feed stream of a carbonyl compound and a stoichiometric excess of phenol; industrial efficiency | GENERAL ELECTRIC COMPANY (US) | 2005-02-22 | — | — | US | disclosed |
| US-20040143142-A1 | Process for manufacture of bisphenols | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143142-A1 | Process for manufacture of bisphenols | REN, ADH1C, ALPP | TSHR 3014/4885ALDH1A1 611/4885TRPA1 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.