Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | EBP | Q15125 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131794 | 0.91 | ADRA1D (0.68) | ADRA1DADRA1AADRA1BGAAHTR1A | |
| SCHEMBL6131799 | 0.89 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL6131937 | 0.89 | ADRA1D (0.60) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL6131869 | 0.89 | ADRA1D (0.60) | ADRA1DADRA1AADRA1BHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6131948 | 0.88 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL6131819 | 0.87 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BHTR1AHTR2C | |
| SCHEMBL6131802 | 0.86 | ADRA1D (0.81) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL6131837 | 0.84 | ALDH1A1 (0.65) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL6131769 | 0.79 | ALDH1A1 (0.67) | ALDH1A1KDM4ETDP1GAASMN1; SMN2 | |
| SCHEMBL6131795 | 0.79 | ALDH1A1 (0.67) | ALDH1A1KDM4ETDP1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |