Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7690877 | 0.99 | ALDH1A1 (0.51) | ALDH1A1KDM4ETDP1MAPK1HTR7 | |
| SCHEMBL6131975 | 0.88 | BCHE (0.57) | ALDH1A1KDM4ETDP1HTR7BCHE | |
| Hydrochloric Acid SCHEMBL6131817 | 0.87 | BCHE (0.56) | ALDH1A1KDM4ETDP1HTR7BCHE | |
| Hydrochloric Acid SCHEMBL6131772 | 0.87 | ALDH1A1 (0.54) | ALDH1A1KDM4ETDP1HTR7BCHE | |
| SCHEMBL6131769 | 0.83 | ALDH1A1 (0.67) | ALDH1A1KDM4ETDP1MAPK1GAA | |
| SCHEMBL6132073 | 0.82 | ALDH1A1 (0.66) | ALDH1A1KDM4ETDP1MAPK1HTR7 | |
| SCHEMBL6131832 | 0.79 | KDM4E (0.63) | ALDH1A1KDM4EMAPK1HTR7BCHE | |
| SCHEMBL6131998 | 0.79 | KDM4E (0.66) | ALDH1A1KDM4ETDP1MAPK1HTR7 | |
| Hydrochloric Acid SCHEMBL6131893 | 0.78 | KDM4E (0.62) | ALDH1A1KDM4EMAPK1HTR7SMN1; SMN2 | |
| SCHEMBL6131790 | 0.78 | ADRA1D (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |