Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131995 | 0.89 | MAPT (0.61) | ALDH1A1SMN1; SMN2KDM4EMAPTNPSR1 | |
| SCHEMBL6131959 | 0.89 | PPARD (0.58) | ALDH1A1SMN1; SMN2KDM4EMAPTNPSR1 | |
| SCHEMBL6131846 | 0.89 | SMN1; SMN2 (0.70) | ALDH1A1SMN1; SMN2KDM4EMAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL6131860 | 0.88 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2KDM4EMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL6132030 | 0.88 | PPARD (0.57) | ALDH1A1SMN1; SMN2KDM4EMAPTNPSR1 | |
| SCHEMBL6131992 | 0.86 | KMT2A (0.60) | ALDH1A1SMN1; SMN2KDM4EMAPTNPSR1 | |
| SCHEMBL6131943 | 0.84 | KDM4E (0.63) | ALDH1A1SMN1; SMN2KDM4EKMT2ADRD2 | |
| SCHEMBL6131795 | 0.84 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2KDM4EMAPTNPSR1 | |
| SCHEMBL6131861 | 0.82 | ALDH1A1 (0.66) | ALDH1A1KDM4EKMT2ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6131911 | 0.82 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2KDM4EMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |