Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6131860 | 0.99 | SMN1; SMN2 (0.60) | MAPTSMN1; SMN2HSD17B10LMNAHPGD | |
| SCHEMBL6131904 | 0.89 | ALDH1A1 (0.56) | MAPTSMN1; SMN2HSD17B10LMNAHPGD | |
| SCHEMBL6131846 | 0.89 | SMN1; SMN2 (0.70) | MAPTSMN1; SMN2HSD17B10LMNAHPGD | |
| SCHEMBL6131943 | 0.88 | KDM4E (0.63) | SMN1; SMN2LMNAALDH1A1KMT2ATSHR | |
| SCHEMBL6131959 | 0.87 | PPARD (0.58) | MAPTSMN1; SMN2HSD17B10LMNAHPGD | |
| SCHEMBL6132010 | 0.86 | GAA (0.62) | SMN1; SMN2ALDH1A1KMT2AMEN1FAAH | |
| SCHEMBL6131830 | 0.86 | KDM4E (0.62) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL6131861 | 0.86 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1FAAHTSHR | |
| SCHEMBL6131992 | 0.86 | KMT2A (0.60) | MAPTSMN1; SMN2LMNAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL6132030 | 0.86 | PPARD (0.57) | MAPTSMN1; SMN2HSD17B10LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |