Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6132030 | 0.99 | PPARD (0.57) | PPARDPPARAALDH1A1NPSR1KDM4E | |
| SCHEMBL6131904 | 0.89 | ALDH1A1 (0.56) | ALDH1A1NPSR1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL6131995 | 0.87 | MAPT (0.61) | ALDH1A1NPSR1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL6131846 | 0.86 | SMN1; SMN2 (0.70) | ALDH1A1NPSR1KDM4ESMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL6131860 | 0.86 | SMN1; SMN2 (0.60) | ALDH1A1NPSR1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL6131992 | 0.83 | KMT2A (0.60) | ALDH1A1NPSR1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL6131943 | 0.80 | KDM4E (0.63) | ALDH1A1KDM4ESMN1; SMN2DRD2DRD4 | |
| SCHEMBL6131795 | 0.79 | ALDH1A1 (0.67) | ALDH1A1NPSR1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL6131920 | 0.79 | KMT2A (0.57) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6131936 | 0.79 | KDM4E (0.55) | ALDH1A1KDM4EDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |