Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131918 | 0.84 | KMT2A (0.55) | KMT2AMEN1KDM4ETP53MAPK1 | |
| SCHEMBL6131995 | 0.83 | MAPT (0.61) | KMT2AMEN1KDM4ETP53MAPK1 | |
| Hydrochloric Acid SCHEMBL6131860 | 0.82 | SMN1; SMN2 (0.60) | KMT2AMEN1KDM4ETP53FAAH | |
| SCHEMBL6131943 | 0.82 | KDM4E (0.63) | KMT2AKDM4EMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6131936 | 0.81 | KDM4E (0.55) | KMT2AMEN1KDM4EMAPK1FAAH | |
| SCHEMBL6131904 | 0.81 | ALDH1A1 (0.56) | KMT2AKDM4EMAPK1PKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL6131827 | 0.81 | KDM4E (0.54) | KMT2AMEN1KDM4EMAPK1FAAH | |
| SCHEMBL6131846 | 0.81 | SMN1; SMN2 (0.70) | KMT2AMEN1KDM4ETP53MAPK1 | |
| SCHEMBL6131830 | 0.81 | KDM4E (0.62) | KMT2AMEN1KDM4EFAAHALDH1A1 | |
| SCHEMBL6132010 | 0.81 | GAA (0.62) | KMT2AMEN1KDM4EFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |