Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | EBP | Q15125 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6132049 | 0.98 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BALDH1A1TSHR | |
| SCHEMBL6131874 | 0.90 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BKMT2AEBP | |
| SCHEMBL6131830 | 0.90 | KDM4E (0.62) | ALDH1A1TSHRKMT2ANPSR1KDM4E | |
| SCHEMBL6131799 | 0.89 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BALDH1A1TSHR | |
| SCHEMBL6131937 | 0.89 | ADRA1D (0.60) | ADRA1DADRA1AADRA1BALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL6131834 | 0.88 | KDM4E (0.60) | ALDH1A1TSHRKMT2ANPSR1KDM4E | |
| SCHEMBL6131925 | 0.88 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BALDH1A1TSHR | |
| SCHEMBL6132007 | 0.88 | ADRA1D (0.76) | ADRA1DADRA1AADRA1BALDH1A1KMT2A | |
| SCHEMBL6131894 | 0.87 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BEBPSIGMAR1 | |
| SCHEMBL6131943 | 0.82 | KDM4E (0.63) | ALDH1A1TSHRKMT2AHTR1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |