Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680831 | 0.88 | DRD2 (0.64) | DRD2SMN1; SMN2MAPK1HSD17B10MEN1 | |
| SCHEMBL6131905 | 0.87 | DRD2 (0.63) | DRD2MAPK1HSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6132064 | 0.87 | DRD2 (0.63) | DRD2SMN1; SMN2MAPK1HSD17B10MEN1 | |
| SCHEMBL5667128 | 0.86 | DRD2 (0.65) | HTTDRD2SMN1; SMN2MAPK1HSD17B10 | |
| Bromide SCHEMBL6132084 | 0.86 | DRD2 (0.61) | DRD2MAPK1HSD17B10MEN1KMT2A | |
| SCHEMBL16884088 | 0.85 | HTT (0.76) | HTTSMN1; SMN2PDE4BMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL5667186 | 0.85 | DRD2 (0.64) | HTTDRD2SMN1; SMN2MAPK1HSD17B10 | |
| SCHEMBL6132003 | 0.79 | KDM4E (0.64) | HTTDRD2PDE4BKMT2ATSHR | |
| SCHEMBL30148770 | 0.78 | DRD2 (0.42) | HTTDRD2SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6132039 | 0.78 | KDM4E (0.63) | HTTDRD2PDE4BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |