Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6131814 | 0.99 | KDM4E (0.61) | KDM4EALDH1A1ALOX15TSHRNPSR1 | |
| SCHEMBL6131832 | 0.92 | KDM4E (0.63) | KDM4EALDH1A1KMT2ABCHEMAOA | |
| Hydrochloric Acid SCHEMBL6131893 | 0.91 | KDM4E (0.62) | KDM4EALDH1A1KMT2ABCHEMAOA | |
| SCHEMBL6131925 | 0.90 | ADRA1D (0.57) | KDM4EALDH1A1ALOX15TSHRNPSR1 | |
| SCHEMBL6131975 | 0.90 | BCHE (0.57) | KDM4EALDH1A1ALOX15TSHRKMT2A | |
| SCHEMBL6131998 | 0.90 | KDM4E (0.66) | KDM4EALDH1A1ALOX15TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL6131817 | 0.89 | BCHE (0.56) | KDM4EALDH1A1ALOX15TSHRKMT2A | |
| SCHEMBL6131769 | 0.89 | ALDH1A1 (0.67) | KDM4EALDH1A1ALOX15TSHRNPSR1 | |
| SCHEMBL6131830 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1ALOX15TSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL6131834 | 0.86 | KDM4E (0.60) | KDM4EALDH1A1ALOX15TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |