Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6131850 | 0.98 | ALDH1A1 (0.55) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL6131887 | 0.83 | ALDH1A1 (0.70) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL22434246 | 0.81 | KDM4E (0.58) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL6131990 | 0.79 | ALDH1A1 (0.71) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL10367458 | 0.79 | HSP90AA1 (0.61) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL22418861 | 0.79 | HTT (0.70) | ALDH1A1HTTKDM4ELMNATSHR | |
| Hydrochloric Acid SCHEMBL6131775 | 0.78 | ALDH1A1 (0.70) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL11828367 | 0.77 | ALDH1A1 (0.60) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL11817430 | 0.76 | ALDH1A1 (0.66) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL7961459 | 0.75 | ALDH1A1 (0.64) | ALDH1A1HTTKDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |