Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817430 | 0.84 | ALDH1A1 (0.66) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL11819047 | 0.83 | ALDH1A1 (0.64) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL22418861 | 0.79 | HTT (0.70) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL11821630 | 0.77 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL11817377 | 0.77 | ALDH1A1 (0.75) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL6131989 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL10367458 | 0.77 | HSP90AA1 (0.61) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL6131990 | 0.77 | ALDH1A1 (0.71) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL13601345 | 0.76 | ALDH1A1 (0.66) | ALDH1A1KDM4ELMNAHTTTSHR | |
| Hydrochloric Acid SCHEMBL6131775 | 0.76 | ALDH1A1 (0.70) | ALDH1A1KDM4ELMNAHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3988457-A | B-NAPHTHYLMETHYL PIPERAZINYL DERIVATIVES | SMITHKLINE CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |