Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | HTT | P42858 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6131775 | 0.99 | ALDH1A1 (0.70) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL6131854 | 0.89 | HTR1A (0.58) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL6907165 | 0.84 | ALDH1A1 (0.69) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL4750766 | 0.83 | ALDH1A1 (0.92) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL5667131 | 0.81 | ALDH1A1 (0.74) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL10367458 | 0.81 | HSP90AA1 (0.61) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL6132095 | 0.81 | ALDH1A1 (0.64) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL6131872 | 0.81 | ALDH1A1 (0.64) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL6131916 | 0.81 | ALDH1A1 (0.67) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL11819047 | 0.81 | ALDH1A1 (0.64) | ALDH1A1HTTKDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |