Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 5/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407804 | 0.78 | SLC6A4 (0.70) | SLC6A4SLC6A2SLC6A3MAPTHTR2A | |
| SCHEMBL30663731 | 0.77 | MAPT (0.56) | MAPT | |
| SCHEMBL10347560 | 0.77 | MAPT (0.56) | MAPT | |
| SCHEMBL29172146 | 0.77 | MAPT (0.63) | MAPT | |
| SCHEMBL28028093 | 0.77 | MAPT (0.58) | MAPT | |
| SCHEMBL31542585 | 0.77 | MAPT (0.58) | MAPT | |
| SCHEMBL5808039 | 0.77 | MAPT (0.58) | MAPT | |
| Hydrochloric Acid SCHEMBL21694039 | 0.75 | MAPT (0.55) | MAPT | |
| SCHEMBL10644162 | 0.75 | MAPT (0.53) | MAPTHTR2A | |
| SCHEMBL8698766 | 0.74 | HRH1 (0.69) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |