Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 5/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28122420 | 0.82 | MAPT (0.55) | SLC6A4SLC6A2SLC6A3MAPTNPSR1 | |
| SCHEMBL3053778 | 0.81 | MAPT (0.53) | SLC6A4SLC6A2SLC6A3MAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL8699695 | 0.79 | DRD2 (0.66) | SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL8698766 | 0.79 | HRH1 (0.69) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL735118 | 0.79 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL8700220 | 0.79 | DRD2 (0.66) | SLC6A4SLC6A2SLC6A3HTR2AALDH1A1 | |
| SCHEMBL5254664 | 0.79 | L3MBTL1 (0.64) | MAPTNPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL31054 | 0.79 | L3MBTL1 (0.84) | MAPTNPSR1L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8387688 | 0.78 | HRH1 (0.67) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6131996 | 0.78 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3MAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772327-B2 | Phenylpropionic acid derivative and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2014-07-08 | — | — | US | disclosed |
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | MORITA KOHEI (JP) | 2013-05-23 | — | — | US | disclosed |
| US-8334314-B2 | Phenylpropionic acid derivative and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20100093819-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |
| US-7316892-B2 | Process of preparing planographic printing plate | KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) | 2008-01-08 | — | — | US | disclosed |
| US-7316892-B2 | Process of preparing planographic printing plate | KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) | 2008-01-08 | — | — | US | disclosed |
| US-20070166647-A1 | Light sensitive planographic printing plate material and planographic printing plate manufacturing process | KONICA MINOLTA MEDICAL & GRAPHIC, INC. | 2007-07-19 | — | — | US | disclosed |
| US-20070166647-A1 | Light sensitive planographic printing plate material and planographic printing plate manufacturing process | KONICA MINOLTA MEDICAL & GRAPHIC, INC. | 2007-07-19 | — | — | US | disclosed |
| US-7192690-B2 | Process of preparing planographic printing plate | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-7192690-B2 | Process of preparing planographic printing plate | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | PLA2G12A, PLA2G4A, PLA2G4B | SLC6A4 1029/4885SLC6A2 2173/4885SLC6A3 2206/4885 |
| US-20100093819-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | PLA2G12A, PLA2G4A, PLA2G4B | SLC6A4 1029/4885SLC6A2 2173/4885SLC6A3 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.