Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 3/20 | 0.42 |
| ▸ | RXRB | P28702 | 3/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302128 | 0.80 | TSHR (0.48) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2222678 | 0.79 | TSHR (0.52) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9695884 | 0.78 | TSHR (0.46) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6688306 | 0.77 | PTGS2 (0.61) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8833485 | 0.77 | TSHR (0.55) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4488292 | 0.77 | PTGS2 (0.61) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL105270 | 0.76 | RXRA (0.62) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL372015 | 0.76 | TSHR (0.60) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL31192242 | 0.76 | TSHR (0.60) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5569785 | 0.75 | TSHR (0.52) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838574-B1 | Dicarba-closo-dodecarborane derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2005-01-04 | — | — | US | disclosed |
| EP-1145718-A1 | DICARBA-closo-DODECABORANE DERIVATIVES | Institute of Medicinal Molecular Design, Inc. (JP) | 2001-10-17 | — | — | EP | disclosed |