Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417929 | 0.88 | KMT2A (0.49) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8648702 | 0.85 | MEN1 (0.54) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL12634965 | 0.85 | MEN1 (0.54) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL6132790 | 0.85 | MEN1 (0.54) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL13313279 | 0.82 | KMT2A (0.49) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL13313284 | 0.78 | LMNA (0.53) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL13349221 | 0.78 | KMT2A (0.37) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL6716155 | 0.78 | KMT2A (0.42) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL27458128 | 0.78 | KMT2A (0.50) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL5417671 | 0.76 | S1PR2 (0.49) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |