Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12634965 | 0.85 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL6132273 | 0.85 | KDM4E (0.54) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8648702 | 0.85 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL11241141 | 0.84 | KMT2A (0.47) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL30123599 | 0.79 | SCN8A (0.41) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL4743329 | 0.78 | ALDH1A1 (0.56) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL27458128 | 0.78 | KMT2A (0.50) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8417929 | 0.76 | KMT2A (0.49) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL3182203 | 0.76 | KMT2A (0.53) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL5591734 | 0.76 | KMT2A (0.49) | MEN1KMT2AKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |