Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CALCA | P06881 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132697 | 0.90 | SIRT2 (0.45) | ALDH1A1POLBSMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL6380498 | 0.88 | HTT (0.45) | ALDH1A1POLBSMN1; SMN2MAPTSIRT2 | |
| SCHEMBL6132374 | 0.87 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL6132596 | 0.87 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL6132375 | 0.87 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL6132744 | 0.86 | USP2 (0.46) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6134915 | 0.86 | ALDH1A1 (0.65) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6135228 | 0.85 | ALDH1A1 (0.67) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6132188 | 0.84 | USP2 (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6232059 | 0.84 | USP2 (0.43) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |