SCHEMBL6132744

SCHEMBL6132744

COC1(C2CCCCC2)CCC(N2CCN(c3ccc(C(=O)O)cc3)CC2)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
KDM4E B2RXH2 5/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 3/20 0.43
HRH3 Q9Y5N1 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
MBTD1 Q05BQ5 1/20 0.42
TP53BP1 Q12888 1/20 0.42
L3MBTL4 Q8NA19 1/20 0.42
L3MBTL3 Q96JM7 1/20 0.42
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
ALOX15 P16050 1/20 0.40
ESRRG P62508 3/20 0.39
ESR1 P03372 2/20 0.39
ESRRA P11474 2/20 0.39
ESRRB O95718 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6132187 0.97 USP2 (0.43) USP2MEN1KMT2AKDM4ETDP1
SCHEMBL6132188 0.97 USP2 (0.43) USP2MEN1KMT2AKDM4ETDP1
SCHEMBL6232059 0.97 USP2 (0.43) USP2MEN1KMT2AKDM4ETDP1
SCHEMBL13099171 0.88 USP2 (0.52) USP2MEN1KMT2AKDM4EALDH1A1
SCHEMBL6132596 0.87 ALDH1A1 (0.43) MEN1KMT2AKDM4ETDP1ALDH1A1
SCHEMBL6132374 0.87 ALDH1A1 (0.43) MEN1KMT2AKDM4ETDP1ALDH1A1
SCHEMBL6132375 0.87 ALDH1A1 (0.43) MEN1KMT2AKDM4ETDP1ALDH1A1
SCHEMBL6132336 0.86 ALDH1A1 (0.51) MEN1KMT2AALDH1A1MAPT
SCHEMBL6133750 0.84 MEN1 (0.39) MEN1KMT2AKDM4ETDP1ALDH1A1
SCHEMBL6133752 0.84 MEN1 (0.39) MEN1KMT2AKDM4ETDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6884868-B1 Cyclic hexapeptides having antibiotic activity FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2005-04-26 US disclosed