Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.40 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.40 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132187 | 1.00 | USP2 (0.43) | USP2MEN1KMT2ACHEK1KDM4E | |
| SCHEMBL6132188 | 1.00 | USP2 (0.43) | USP2MEN1KMT2ACHEK1KDM4E | |
| SCHEMBL6132744 | 0.97 | USP2 (0.46) | USP2MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL6132596 | 0.91 | ALDH1A1 (0.43) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL6132374 | 0.91 | ALDH1A1 (0.43) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL6132375 | 0.91 | ALDH1A1 (0.43) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL6133752 | 0.87 | MEN1 (0.39) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL6133750 | 0.87 | MEN1 (0.39) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL13099171 | 0.85 | USP2 (0.52) | USP2MEN1KMT2ACHEK1KDM4E | |
| SCHEMBL6133874 | 0.84 | ALDH1A1 (0.43) | MEN1KMT2AKDM4EALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259535-B1 | CYCLIC HEXAPEPTIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-04-13 | — | — | EP | disclosed |