Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MGAM | O43451 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SI | P14410 | 3/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324945 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL7324936 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL6134795 | 0.80 | MEN1 (0.49) | HRH3ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL6134791 | 0.80 | MEN1 (0.49) | HRH3ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL1645940 | 0.79 | L3MBTL1 (0.49) | HRH3ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL12082268 | 0.75 | L3MBTL1 (0.50) | HRH3ALDH1A1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL7316756 | 0.75 | KDM4E (0.51) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL8160141 | 0.74 | KDM4E (0.54) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL7325194 | 0.73 | GAA (0.53) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL6134446 | 0.73 | KDM4E (0.51) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |