Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MGAM | O43451 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | SI | P14410 | 4/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324945 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNAKDM4ERAB9A | |
| SCHEMBL6132453 | 0.85 | HRH3 (0.43) | ALDH1A1SMN1; SMN2LMNAKDM4ERAB9A | |
| SCHEMBL6132936 | 0.79 | CSNK2A2 (0.48) | ALDH1A1RAB9AMAPTCSNK2A2CSNK2B | |
| SCHEMBL6132938 | 0.79 | CSNK2A2 (0.48) | ALDH1A1RAB9AMAPTCSNK2A2CSNK2B | |
| SCHEMBL7316756 | 0.77 | KDM4E (0.51) | ALDH1A1SMN1; SMN2LMNAKDM4ERAB9A | |
| SCHEMBL6132711 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNAKDM4ERAB9AMAPT | |
| SCHEMBL6132709 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNAKDM4ERAB9AMAPT | |
| SCHEMBL8160141 | 0.76 | KDM4E (0.54) | ALDH1A1SMN1; SMN2LMNAKDM4ERAB9A | |
| SCHEMBL7325194 | 0.75 | GAA (0.53) | ALDH1A1SMN1; SMN2LMNAKDM4ERAB9A | |
| SCHEMBL7312437 | 0.74 | KDM4E (0.51) | ALDH1A1SMN1; SMN2LMNAKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |