Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132212 | 0.90 | LMNA (0.34) | ALDH1A1CYP3A4THRBMAPK1MAPT | |
| SCHEMBL6132332 | 0.88 | PDE4A (0.33) | ALDH1A1CYP3A4THRBMAPK1MAPT | |
| SCHEMBL18878206 | 0.71 | — | — | |
| SCHEMBL7783061 | 0.70 | MEN1 (0.33) | ALDH1A1CYP3A4 | |
| SCHEMBL8488027 | 0.69 | CYP3A4 (0.37) | ALDH1A1CYP3A4THRBMAPK1MAPT | |
| SCHEMBL3039523 | 0.67 | MEN1 (0.34) | ALDH1A1 | |
| SCHEMBL12389946 | 0.67 | HSD11B1 (0.39) | HSD11B1 | |
| SCHEMBL15897356 | 0.67 | CYP3A4 (0.35) | ALDH1A1CYP3A4THRBMAPK1MAPT | |
| SCHEMBL7735455 | 0.66 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL12389949 | 0.66 | HSD11B1 (0.35) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |