⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132615 | 0.78 | ADRB1 (0.44) | — | |
| SCHEMBL4409694 | 0.77 | GNAO1 (0.43) | — | |
| SCHEMBL6132345 | 0.72 | SLC6A4 (0.34) | — | |
| SCHEMBL6132360 | 0.72 | SLC6A4 (0.34) | — | |
| SCHEMBL7410627 | 0.70 | GNAO1 (0.38) | — | |
| SCHEMBL16359545 | 0.69 | ITGB3 (0.42) | — | |
| SCHEMBL22297174 | 0.69 | ITGB3 (0.40) | — | |
| SCHEMBL18056826 | 0.68 | — | — | |
| SCHEMBL1308005 | 0.67 | GNAO1 (0.39) | — | |
| SCHEMBL6043580 | 0.66 | SLC6A4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |