Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 8/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 8/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132721 | 0.98 | RARB (0.59) | RARBTP53TSHRPLA2G4BMKNK1 | |
| SCHEMBL6132847 | 0.91 | MKNK1 (0.51) | RARBTP53TSHRMKNK1MKNK2 | |
| SCHEMBL6133900 | 0.82 | MKNK1 (0.45) | RARBMKNK1MKNK2FYNCSNK2A2 | |
| SCHEMBL6132537 | 0.81 | MKNK1 (0.52) | TSHRMKNK1MKNK2FYN | |
| SCHEMBL7321701 | 0.81 | MKNK1 (0.61) | MKNK1MKNK2FYN | |
| SCHEMBL7324612 | 0.81 | MKNK1 (0.61) | MKNK1MKNK2FYN | |
| SCHEMBL7318292 | 0.81 | MKNK1 (0.61) | MKNK1MKNK2FYN | |
| SCHEMBL7324198 | 0.81 | MKNK1 (0.61) | MKNK1MKNK2FYN | |
| SCHEMBL7322460 | 0.81 | MKNK1 (0.53) | MKNK1MKNK2FYN | |
| SCHEMBL6539365 | 0.80 | NR1H4 (0.70) | RARBTP53TSHRPLA2G4BCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |