Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 4/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7325659 | 0.92 | SIRT2 (0.46) | LMNASIRT2SIRT1KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7324043 | 0.92 | MTOR (0.42) | LMNASIRT2SIRT1MAPTL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL7317609 | 0.91 | TP53 (0.41) | LMNASIRT2SIRT1ALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL7320929 | 0.87 | ALDH1A1 (0.42) | LMNASIRT2SIRT1ALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL6132999 | 0.87 | SIRT2 (0.40) | LMNASIRT2SIRT1MAPTPOLB | |
| Trifluoroacetic Acid SCHEMBL6132355 | 0.86 | MAPT (0.38) | LMNAALDH1A1MAPTPOLBMEN1 | |
| Trifluoroacetic Acid SCHEMBL6539243 | 0.86 | TP53 (0.56) | KDM4EMAPTSMN1; SMN2RECQLTP53 | |
| Trifluoroacetic Acid SCHEMBL6132991 | 0.86 | ALDH1A1 (0.39) | LMNAALDH1A1MAPTL3MBTL1MEN1 | |
| Trifluoroacetic Acid SCHEMBL6134998 | 0.85 | SIRT2 (0.40) | LMNASIRT2SIRT1ALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL7323795 | 0.84 | CA12 (0.56) | KDM4EALDH1A1MAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |