Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HAT1 | O14929 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16708779 | 0.82 | SMN1; SMN2 (0.46) | PDE10ASMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL7469718 | 0.80 | ALDH1A1 (0.40) | PDE10ASMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL3509780 | 0.78 | PDE10A (0.45) | PDE10ASMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL22267907 | 0.76 | SIGMAR1 (0.50) | PDE10ASMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL22267906 | 0.74 | EP300 (0.43) | PDE10ASMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL4509000 | 0.74 | — | — | |
| SCHEMBL30600853 | 0.73 | NPC1 (0.46) | PDE10ASMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL17273755 | 0.73 | HCAR2 (0.49) | SMN1; SMN2ALDH1A1GAANPC1RAB9A | |
| SCHEMBL8342570 | 0.71 | — | — | |
| SCHEMBL7941493 | 0.71 | PDE8B (0.38) | PDE10ASMN1; SMN2ALDH1A1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004094-A1 | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| WO-2004101571-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004094-A1 | Cephem compounds | CEP170, C1S, CEPT1 | PDE10A 635/4885SMN1; SMN2 1176/4885ALDH1A1 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.