Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.51 |
| ▸ | WNT3A | P56704 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6134224 | 0.88 | HTT (0.52) | PDE4DTSHRCTNNB1WNT3AMAPT | |
| SCHEMBL6134073 | 0.83 | PDE4D (0.45) | PDE4DTSHRALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6135277 | 0.82 | CES2 (0.41) | PDE4DMAPTNPC1LMNAHTT | |
| SCHEMBL6133543 | 0.81 | NPC1 (0.54) | MAPTNPC1LMNAHTTCA1 | |
| SCHEMBL5799347 | 0.81 | NPC1 (0.48) | TSHRCTNNB1WNT3AMAPTNPC1 | |
| SCHEMBL6133870 | 0.79 | GSK3B (0.43) | MAPTNPC1LMNAHTTKMT2A | |
| SCHEMBL6133460 | 0.79 | NPC1 (0.50) | MAPTNPC1LMNAHTTKMT2A | |
| SCHEMBL6134151 | 0.79 | NNMT (0.45) | TSHRMAPTCYP3A4NPC1LMNA | |
| SCHEMBL6134053 | 0.79 | CES2 (0.51) | TSHRCTNNB1WNT3AMAPTNPC1 | |
| SCHEMBL6134193 | 0.79 | CTNNB1 (0.50) | CTNNB1WNT3AMAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043315-A1 | Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them | ASTELLAS PHARMA INC. (JP) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043315-A1 | Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them | ADORA2B, ADORA2A, ADORA1 | PDE4D 926/4885TSHR 1977/4885CTNNB1 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.