SCHEMBL6133750

SCHEMBL6133750

CON(C)C(=O)c1ccc(-c2ccc(N3CCN(C4CCC(OC)(C5CCCCC5)CC4)CC3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
HRH3 Q9Y5N1 4/20 0.37
KDM4E B2RXH2 4/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
MBTD1 Q05BQ5 1/20 0.36
TP53BP1 Q12888 1/20 0.36
L3MBTL4 Q8NA19 1/20 0.36
L3MBTL3 Q96JM7 1/20 0.36
ALDH1A1 P00352 2/20 0.36
GPR119 Q8TDV5 2/20 0.35
ITGB3 P05106 1/20 0.34
ITGA2B P08514 1/20 0.34
KDM2B Q8NHM5 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP9 P14780 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6133752 1.00 MEN1 (0.39) MEN1KMT2AESR1ESR2HRH3
SCHEMBL6132187 0.87 USP2 (0.43) MEN1KMT2AESR1ESR2HRH3
SCHEMBL6132188 0.87 USP2 (0.43) MEN1KMT2AESR1ESR2HRH3
SCHEMBL6232059 0.87 USP2 (0.43) MEN1KMT2AESR1ESR2HRH3
SCHEMBL6132374 0.86 ALDH1A1 (0.43) MEN1KMT2AESR1ESR2HRH3
SCHEMBL6132375 0.86 ALDH1A1 (0.43) MEN1KMT2AESR1ESR2HRH3
SCHEMBL6132596 0.86 ALDH1A1 (0.43) MEN1KMT2AESR1ESR2HRH3
SCHEMBL6132744 0.84 USP2 (0.46) MEN1KMT2AESR1HRH3KDM4E
SCHEMBL6134823 0.81 HRH3 (0.38) HRH3GPR119
SCHEMBL6133874 0.80 ALDH1A1 (0.43) MEN1KMT2AHRH3KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050004014-A1 Fungicides, microbiocides; glucanase inhibitor; prophylaxis, therapy for pneumocystis infections in humans, animals FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2005-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050004014-A1 Fungicides, microbiocides; glucanase inhibitor; prophylaxis, therapy for pneumocystis infections in humans, animals MAN2B1, MAN2A1, MANBA MEN1 1376/4885KMT2A 4054/4885ESR1 4816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.