Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MDH2 | P40926 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705100 | 0.91 | KDM4E (0.66) | ALDH1A1KDM4EMAPTHSD17B10HTR2C | |
| SCHEMBL7864917 | 0.80 | HTR6 (0.81) | ALDH1A1KDM4EMAPTHSD17B10HTR2C | |
| SCHEMBL31640013 | 0.79 | HTR6 (0.52) | HTR2CHTR6PRMT5 | |
| SCHEMBL16801767 | 0.79 | KDM4E (0.56) | ALDH1A1KDM4EMAPTHSD17B10HTR2C | |
| Hydrochloric Acid SCHEMBL29923085 | 0.78 | PRMT5 (0.62) | MAPTHTR2CHTR6CYP1A2PRMT5 | |
| SCHEMBL12874806 | 0.77 | KDM4E (0.48) | ALDH1A1KDM4EMAPTHSD17B10HTR2C | |
| SCHEMBL4672600 | 0.77 | PRMT5 (0.64) | MAPTHTR2CHTR6CYP1A2PRMT5 | |
| SCHEMBL16801579 | 0.76 | PRMT5 (0.53) | ALDH1A1MAPTDRD2PRMT5HPGD | |
| SCHEMBL29379037 | 0.75 | KDM4E (1.00) | ALDH1A1KDM4EMAPTHSD17B10HTR2C | |
| SCHEMBL653742 | 0.75 | KDM4E (1.00) | ALDH1A1KDM4EMAPTHSD17B10HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050245540-A1 | New methods | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245540-A1 | New methods | TGFB1, TGFBR1, TGFB2 | ALDH1A1 885/4885KDM4E 3172/4885MAPT 4269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.