Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902700 | 1.00 | HTR6 (0.63) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| Hydrochloric Acid SCHEMBL31598665 | 0.98 | HTR6 (0.61) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL1507120 | 0.98 | HTR6 (0.65) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL11166747 | 0.95 | HTR6 (0.56) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL477067 | 0.93 | HTR6 (0.67) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL455527 | 0.93 | HTR6 (0.67) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL28008874 | 0.93 | HTR6 (0.67) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL524430 | 0.93 | HTR6 (0.59) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL451992 | 0.93 | HTR6 (0.64) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL1267270 | 0.93 | HTR6 (0.64) | HTR6HPGDKMT2ASMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140275010-A1 | QUATERNARY SALTS | ZHENG GUO ZHU (US) | 2014-09-18 | — | — | US | disclosed |
| US-20050261177-A1 | Compound | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261177-A1 | Compound | MANBA, MAN2B1, MAN2A1 | HTR6 4847/4885HPGD 3433/4885KMT2A 4492/4885 |
| US-20140275010-A1 | QUATERNARY SALTS | TP53, VHL, SF3B5 | HTR6 4806/4885HPGD 2532/4885KMT2A 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.